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Solosos III was a planet in the Demilitarized Zone between the Cardassian Union and the Untied Federation of Planets. By 2373, it was home to a Maquis colony.

That year, Captain Benjamin Sisko used the USS Defiant to poison the planet's atmosphere with trilithium, in response to Michael Eddington's use of biogenic weapons against Cardassian colonies on Quatal and Veloz Prime. The Maquis began an evacuation shortly thereafter, and the planet was settled by refugees displaced from the two Cardassian colonies. (DS9: "For the Uniform")

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