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Slaybis IV was a Class M planet in the Slaybis system, in the Demilitarized Zone between the Cardassian Union and the United Federation of Planets. It had at least three moons, and was the site of a human colony.

Slaybis Central was the name of the colony's capital city.

In 2371, Slaybis IV was attacked and nearly destroyed by Tharia ch'Ren, a rogue member of the Maquis. (VOY novel: The Third Artifact)